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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP35 All Species: 20.91
Human Site: S252 Identified Species: 35.38
UniProt: Q8NFH5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NFH5 NP_612142.2 326 34774 S252 D K S V M E S S D R C A L S S
Chimpanzee Pan troglodytes XP_001160265 337 36129 S263 D K S V M E S S D R C A L S S
Rhesus Macaque Macaca mulatta XP_001102848 326 34769 S252 D K S V M E S S D R C A L S S
Dog Lupus familis XP_535992 406 43346 N332 D K S V M E N N D R C A L S S
Cat Felis silvestris
Mouse Mus musculus Q8R4R6 325 34767 S251 D K N V M E N S D R G V L S S
Rat Rattus norvegicus Q68FY1 325 34783 S251 D K N V M E N S D R G V L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516155 235 24557 D162 T S E D H L D D T W V T V F G
Chicken Gallus gallus XP_421854 325 34473 F251 D K S V M E N F E R S S A S S
Frog Xenopus laevis NP_001085157 318 33973 Y243 D K S V M E A Y E K V T T P S
Zebra Danio Brachydanio rerio Q6P6X9 308 32866 M234 P C I D K S V M E S L D K G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573314 331 35081 V256 I I A G N V M V G V S R C T D
Honey Bee Apis mellifera XP_396287 584 64120 S510 A C N G N I V S G S I M I G V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200424 554 60750 G270 D K G V M S G G T S D S Y G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03790 475 52600 Q329 L S K S R A L Q E N G I I M N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.2 99.6 78 N.A. 92.9 94.4 N.A. 63.1 83.4 73.3 71.4 N.A. 27.1 22.6 N.A. 24.3
Protein Similarity: 100 95.8 100 79.3 N.A. 96 97.2 N.A. 65.9 91.4 84 82.2 N.A. 45 32.5 N.A. 36.4
P-Site Identity: 100 100 100 86.6 N.A. 73.3 73.3 N.A. 0 60 46.6 6.6 N.A. 0 6.6 N.A. 26.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 6.6 80 66.6 13.3 N.A. 13.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 8 8 0 0 0 0 29 8 0 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 29 0 8 0 0 % C
% Asp: 65 0 0 15 0 0 8 8 43 0 8 8 0 0 8 % D
% Glu: 0 0 8 0 0 58 0 0 29 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 15 0 0 8 8 15 0 22 0 0 22 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 0 8 0 0 0 0 8 8 15 0 0 % I
% Lys: 0 65 8 0 8 0 0 0 0 8 0 0 8 0 0 % K
% Leu: 8 0 0 0 0 8 8 0 0 0 8 0 43 0 0 % L
% Met: 0 0 0 0 65 0 8 8 0 0 0 8 0 8 0 % M
% Asn: 0 0 22 0 15 0 29 8 0 8 0 0 0 0 8 % N
% Pro: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 0 50 0 8 0 0 0 % R
% Ser: 0 15 43 8 0 15 22 43 0 22 15 15 0 50 65 % S
% Thr: 8 0 0 0 0 0 0 0 15 0 0 15 8 8 0 % T
% Val: 0 0 0 65 0 8 15 8 0 8 15 15 8 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _